1 Table of Contents
1 Table of Contents 2
1.1 List of Tables 17
1.2 List of Figures 36
2 Introduction 37
2.1 Advanced Wound Management Overview 37
3 Products under Development 40
3.1 Advanced Wound Management - Pipeline Products by Stage of Development 40
3.2 Advanced Wound Management - Pipeline Products by Segment 41
3.3 Advanced Wound Management - Pipeline Products by Territory 42
3.4 Advanced Wound Management - Pipeline Products by Regulatory Path 44
3.5 Advanced Wound Management - Pipeline Products by Estimated Approval Date 45
3.6 Advanced Wound Management - Ongoing Clinical Trials 46
4 Advanced Wound Management - Pipeline Products under Development by Companies 47
4.1 Advanced Wound Management Companies - Pipeline Products by Stage of Development 47
4.2 Advanced Wound Management - Pipeline Products by Stage of Development 53
5 Advanced Wound Management Companies and Product Overview 61
5.1 3QMatrix, Inc. Company Overview 61
5.2 3S BioMedical, Inc. Company Overview 62
5.3 Abeona Therapeutics Inc Company Overview 64
5.4 Acelity L.P. Inc. Company Overview 66
5.5 Advanced Medical Solutions Group plc Company Overview 72
5.6 Advanced Plasma Products, Inc. Company Overview 75
5.7 AGAM Biological Products Company Overview 76
5.8 Agenta Biotechnologies Inc Company Overview 77
5.9 Akeso Biomedical, Inc. Company Overview 80
5.10 Alafair Biosciences Inc Company Overview 81
5.11 Alliance Pharma Inc Company Overview 84
5.12 Alliqua BioMedical Inc Company Overview 85
5.13 Amarantus Bioscience Holdings Inc Company Overview 87
5.14 AnGes MG Inc Company Overview 89
5.15 Angiotech Pharmaceuticals Inc Company Overview 91
5.16 Anika Therapeutics Inc Company Overview 92
5.17 ApoPharma Inc Company Overview 96
5.18 ARC Medical Devices Inc. Company Overview 97
5.19 Aroa Biosurgery Ltd Company Overview 98
5.20 Arsenal Medical Inc Company Overview 100
5.21 Arteriocyte Medical Systems Inc Company Overview 104
5.22 Asana Medical, Inc. Company Overview 109
5.23 Aspen Surgical Products Company Overview 110
5.24 Avita Medical Ltd Company Overview 111
5.25 Axcelon Biopolymers Corp. Company Overview 114
5.26 Baxter International Inc Company Overview 115
5.27 Bayer HealthCare AG Company Overview 117
5.28 BioCure, Inc. Company Overview 119
5.29 Biomendics, LLC Company Overview 122
5.30 BioPhotas, Inc. Company Overview 123
5.31 BioRegenerative Sciences, Inc. Company Overview 124
5.32 BioSurfaces, Inc. Company Overview 126
5.33 Biotec Pharmacon ASA Company Overview 128
5.34 BioTime Inc Company Overview 131
5.35 Biovation LLC Company Overview 133
5.36 botiss dental GmbH Company Overview 134
5.37 Brigham and Women's Hospital Company Overview 137
5.38 Camurus AB Company Overview 138
5.39 CelaCare Technologies, Inc. Company Overview 140
5.40 CellTran Limited (Inactive) Company Overview 143
5.41 Ceramicos Para Aplicacoes Medicas Lda Company Overview 144
5.42 Chi2Gel Ltd. Company Overview 145
5.43 Clearbridge Accelerator Pte Ltd Company Overview 146
5.44 CMB Science Inc. Company Overview 147
5.45 Coloplast A/S Company Overview 148
5.46 Coltrix Biomedical Company Overview 154
5.47 Consejo Superior de Investigaciones Cientificas Company Overview 155
5.48 Conversion Energy Enterprises Company Overview 156
5.49 Corium International Inc Company Overview 157
5.50 CorMedix Inc Company Overview 159
5.51 Covalon Technologies Ltd Company Overview 161
5.52 DeCell Technologies Inc Company Overview 177
5.53 Dipromed Srl Company Overview 178
5.54 Divya Laboratories Company Overview 179
5.55 Drexel University Company Overview 180
5.56 Dynamic Techno Medicals Company Overview 182
5.57 Edixomed Ltd Company Overview 183
5.58 EnzySurge Ltd Company Overview 189
5.59 Eqalix Inc Company Overview 192
5.60 E-QURE Corp. Company Overview 196
5.61 EternoGen, LLC Company Overview 198
5.62 European Medical Contract Manufacturing B.V. Company Overview 199
5.63 Factor Therapeutics Ltd Company Overview 201
5.64 Fundacion para la Investigacion Biomedica del Hospital Gregorio Maranon Company Overview 205
5.65 FzioMed Inc Company Overview 206
5.66 Genewel Co Ltd Company Overview 207
5.67 Genzyme Corp Company Overview 209
5.68 Giltech Ltd Company Overview 211
5.69 Harbor MedTech, Inc. Company Overview 212
5.70 Healagenics, Inc. Company Overview 215
5.71 Hemostasis, LLC Company Overview 216
5.72 Histocell SL Company Overview 217
5.73 Holista CollTech Ltd Company Overview 219
5.74 HyperBranch Medical Technology, Inc. Company Overview 220
5.75 Ilika plc Company Overview 221
5.76 Imbed Biosciences, Inc. Company Overview 222
5.77 Indian Institute of Technology, Kanpur Company Overview 224
5.78 Innocoll Technologies Ltd Company Overview 225
5.79 Integra LifeSciences Corp Company Overview 231
5.80 InVivo Therapeutics Corporation Company Overview 232
5.81 IPI Singapore Company Overview 234
5.82 Jellagen Pty Ltd Company Overview 236
5.83 John Hopkins University Company Overview 237
5.84 KeraCure, Inc. (Inactive) Company Overview 239
5.85 KeraNetics, LLC Company Overview 241
5.86 Khorionyx Company Overview 244
5.87 Klox Technologies Inc Company Overview 245
5.88 Kyeron BV Company Overview 249
5.89 Lattice Biologics Ltd Company Overview 250
5.90 Leiden University Company Overview 252
5.91 Luna Innovations Inc Company Overview 253
5.92 Magen OrthoMed Ltd Company Overview 255
5.93 Magenta Medical Inc Company Overview 258
5.94 Maxigen Biotech Inc Company Overview 262
5.95 Medtric Biotech, LLC Company Overview 264
5.96 Medtronic plc Company Overview 266
5.97 Menodys Inc. Company Overview 268
5.98 MiMedx Group Inc Company Overview 269
5.99 MxBiodevices, LLC. Company Overview 271
5.100 Nanotherapeutics Inc Company Overview 272
5.101 NanoVibronix Inc Company Overview 273
5.102 National Cheng-Kung University Hospital Company Overview 274
5.103 Neotherix Ltd Company Overview 275
5.104 Newcastle University Company Overview 278
5.105 NitricGen, Inc. Company Overview 279
5.106 Northwestern University Company Overview 280
5.107 NovaBay Pharmaceuticals Inc Company Overview 284
5.108 NovelMed Therapeutics Inc Company Overview 286
5.109 Novyx Technologies LLC Company Overview 287
5.110 Nuvo Pharmaceuticals Inc Company Overview 288
5.111 Old Dominion University Company Overview 289
5.112 Oxtex Ltd Company Overview 290
5.113 OxyBand Technologies Inc Company Overview 291
5.114 Pathfinder Cell Therapy Inc Company Overview 292
5.115 Perfuzia Medical, Inc. Company Overview 293
5.116 Pernix Therapeutics Holdings Inc Company Overview 295
5.117 Pharmagenix AG Company Overview 297
5.118 Piramal Enterprises Ltd Company Overview 298
5.119 PlasMedica Technologies Limited Company Overview 300
5.120 Plurogen Therapeutics Inc Company Overview 306
5.121 PolyActiva Pty Ltd Company Overview 307
5.122 PolyNovo Biomaterials Pty Ltd Company Overview 308
5.123 Protein Polymer Technologies Inc (Inactive) Company Overview 312
5.124 Q Care Medical Services BVBA Company Overview 314
5.125 Quick-Med Technologies, Inc. Company Overview 316
5.126 RenovaCare, Inc. Company Overview 319
5.127 Resultados y Calidad del Sistema Sanitario Publico de Andalucia Company Overview 320
5.128 Rimon Therapeutics Ltd Company Overview 321
5.129 Rutgers The State University of New Jersey Company Overview 323
5.130 SANUWAVE Health Inc Company Overview 324
5.131 Sarasota Medical Products Inc Company Overview 328
5.132 Shire Plc Company Overview 331
5.133 Siemens Healthcare GmbH Company Overview 333
5.134 Sinclair Pharma PLC Company Overview 334
5.135 Sintact Medical Systems, LLC Company Overview 335
5.136 SIRIM Berhad Company Overview 336
5.137 Smith & Nephew Plc Company Overview 337
5.138 STB Lifesaving Technologies Company Overview 339
5.139 Stratatech Corp Company Overview 340
5.140 Stratpharma AG Company Overview 341
5.141 Taxus Cardium Pharmaceuticals Group Inc Company Overview 344
5.142 Tel Aviv Sourasky Medical Center Company Overview 346
5.143 Tel Aviv University Company Overview 348
5.144 Tenax Therapeutics Inc Company Overview 350
5.145 The Chinese University of Hong Kong Company Overview 351
5.146 The University of Queensland Company Overview 352
5.147 Tissue Regenix Ltd Company Overview 354
5.148 Trans-Technologies Ltd Company Overview 356
5.149 Trinity College Dublin Company Overview 357
5.150 ULURU Inc Company Overview 358
5.151 Universitat Politecnica de Catalunya Company Overview 360
5.152 Universite De Lyon Company Overview 361
5.153 University of Akron Company Overview 362
5.154 University of Bath Company Overview 363
5.155 University of California San Diego Company Overview 365
5.156 University of Florida Company Overview 366
5.157 University of Glasgow Company Overview 367
5.158 University of South Florida Company Overview 368
5.159 University of Texas at Arlington Company Overview 370
5.160 University of Washington Company Overview 371
5.161 University of Wisconsin Madison Company Overview 372
5.162 Vancive Medical Technologies Company Overview 374
5.163 Vascular Solutions, Inc. Company Overview 376
5.164 Ventrix Inc Company Overview 378
5.165 Worcester Polytechnic Institute Company Overview 380
5.166 Zeomedix, LLC Company Overview 383
5.167 ZetrOZ, Inc. Company Overview 384
6 Advanced Wound Management- Recent Developments 385
6.1 Nov 30, 2016: Graham Baker appointed Chief Financial Officer 385
6.2 Nov 29, 2016: NIH Funds Clinical Trial To Test Device That Heals Wounds With Ultrasound 385
6.3 Nov 28, 2016: Misonix Reports Nasdaq's Acceptance of Its Plan to Regain Listing Compliance 387
6.4 Nov 22, 2016: Peer-reviewed Publication on the use of Grafix in High-Risk Peripheral Arterial Disease Patients with Treatment Refractory Ulcerations Demonstrating Durable Wound Closure 387
6.5 Nov 22, 2016: Medtronic Reports Second Quarter Financial Results 388
6.6 Nov 22, 2016: Innocoll Announces Third Quarter 2016 Financial and Operating Results and Provides Corporate Update 391
6.7 Nov 22, 2016: Pernix appoints new board member 393
6.8 Nov 22, 2016: Shire to Establish Rare Disease Innovation Hub in Cambridge, Mass. 393
6.9 Nov 21, 2016: Osiris Provides Update Regarding NASDAQ Listing Matters 394
7 Appendix 733
7.1 Methodology 733
7.2 About GlobalData 736
7.3 Contact Us 736
7.4 Disclaimer 736

1.1 List of Tables
Table 1: Advanced Wound Management - Pipeline Products by Stage of Development 44
Table 2: Advanced Wound Management - Pipeline Products by Segment 45
Table 3: Advanced Wound Management - Pipeline Products by Territory 46
Table 4: Advanced Wound Management - Pipeline Products by Regulatory Path 48
Table 5: Advanced Wound Management - Pipeline Products by Estimated Approval Date 49
Table 6: Advanced Wound Management - Ongoing Clinical Trials 50
Table 7: Advanced Wound Management Companies - Pipeline Products by Stage of Development 51
Table 8: Advanced Wound Management - Pipeline Products by Stage of Development 57
Table 9: 3QMatrix, Inc. Pipeline Products & Ongoing Clinical Trials Overview 65
Table 10: Bi-layer Dressing - Product Status 65
Table 11: Bi-layer Dressing - Product Description 65
Table 12: 3S BioMedical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 66
Table 13: Resorpor HydroMatrix Tissue Repair - Product Status 66
Table 14: Resorpor HydroMatrix Tissue Repair - Product Description 66
Table 15: Resorpor RapiMatrix Tissue Repair - Product Status 67
Table 16: Resorpor RapiMatrix Tissue Repair - Product Description 67
Table 17: Abeona Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 68
Table 18: BenzaGard - Product Status 68
Table 19: BenzaGard - Product Description 69
Table 20: Acelity L.P. Inc. Pipeline Products & Ongoing Clinical Trials Overview 70
Table 21: BIOSORB Gelling Fiber Dressing - Silver - Product Status 70
Table 22: BIOSORB Gelling Fiber Dressing - Silver - Product Description 71
Table 23: Negative Pressure Regenerative Medicine - Chronic Wounds - Product Status 71
Table 24: Negative Pressure Regenerative Medicine - Chronic Wounds - Product Description 72
Table 25: Strattice For Dura Repair - Product Status 72
Table 26: Strattice For Dura Repair - Product Description 72
Table 27: Strattice For Facelift - Product Status 73
Table 28: Strattice For Facelift - Product Description 73
Table 29: Strattice For Lumpectomy Reconstruction - Product Status 73
Table 30: Strattice For Lumpectomy Reconstruction - Product Description 74
Table 31: Strattice For Rhinoplasty - Product Status 74
Table 32: Strattice For Rhinoplasty - Product Description 74
Table 33: Strattice For Stoma Reinforcement - Product Status 75
Table 34: Strattice For Stoma Reinforcement - Product Description 75
Table 35: Advanced Medical Solutions Group plc Pipeline Products & Ongoing Clinical Trials Overview 76
Table 36: ActivHeal Atraumatic Foam Dressing - Product Status 76
Table 37: ActivHeal Atraumatic Foam Dressing - Product Description 77
Table 38: Post-operative Surgical Dressing - Product Status 77
Table 39: Post-operative Surgical Dressing - Product Description 77
Table 40: Reinforced Collagen - Product Status 78
Table 41: Reinforced Collagen - Product Description 78
Table 42: Advanced Plasma Products, Inc. Pipeline Products & Ongoing Clinical Trials Overview 79
Table 43: Atmospheric Plasma Wound Applicator Device - Product Status 79
Table 44: Atmospheric Plasma Wound Applicator Device - Product Description 79
Table 45: AGAM Biological Products Pipeline Products & Ongoing Clinical Trials Overview 80
Table 46: Wound Dressing Pad - Product Status 80
Table 47: Wound Dressing Pad - Product Description 80
Table 48: Agenta Biotechnologies Inc Pipeline Products & Ongoing Clinical Trials Overview 81
Table 49: Biologic Loaded Membrane - Wound Healing - Product Status 81
Table 50: Biologic Loaded Membrane - Wound Healing - Product Description 81
Table 51: Biologically Loaded Dermal Substitute - Product Status 82
Table 52: Biologically Loaded Dermal Substitute - Product Description 82
Table 53: Wound Dressing - Oral Wounds - Product Status 82
Table 54: Wound Dressing - Oral Wounds - Product Description 83
Table 55: Akeso Biomedical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 84
Table 56: Silk Scaffold - Product Status 84
Table 57: Silk Scaffold - Product Description 84
Table 58: Alafair Biosciences Inc Pipeline Products & Ongoing Clinical Trials Overview 85
Table 59: Alafair Bilayer - Product Status 85
Table 60: Alafair Bilayer - Product Description 86
Table 61: Alafair Injectable Gel - Product Status 86
Table 62: Alafair Injectable Gel - Product Description 86
Table 63: Alafair Membrane - Product Status 87
Table 64: Alafair Membrane - Product Description 87
Table 65: Alliance Pharma Inc Pipeline Products & Ongoing Clinical Trials Overview 88
Table 66: Aloclair Ultra - Product Status 88
Table 67: Aloclair Ultra - Product Description 88
Table 68: Alliqua BioMedical Inc Pipeline Products & Ongoing Clinical Trials Overview 89
Table 69: Tissue Repair Scaffold - Product Status 89
Table 70: Tissue Repair Scaffold - Product Description 90
Table 71: Amarantus Bioscience Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 91
Table 72: PermaDerm - Product Status 91
Table 73: PermaDerm - Product Description 92
Table 74: Amarantus Bioscience Holdings Inc - Ongoing Clinical Trials Overview 92
Table 75: PermaDerm - Evaluation of Autologous Engineered Skin Substitute (ESS-W) Compared to Meshed, Split-thickness Autograft (AG) for Treatment of Deep Partial- and Full-thickness Thermal Burn Wounds in Adult Patients 92
Table 76: AnGes MG Inc Pipeline Products & Ongoing Clinical Trials Overview 93
Table 77: CUREPEPTIN - Product Status 93
Table 78: CUREPEPTIN - Product Description 94
Table 79: Angiotech Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 95
Table 80: Adhibit - Product Status 95
Table 81: Adhibit - Product Description 95
Table 82: Anika Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 96
Table 83: Cronofill - Product Status 96
Table 84: Cronofill - Product Description 97
Table 85: HYAFF Barrier Film - Product Status 97
Table 86: HYAFF Barrier Film - Product Description 97
Table 87: HYAFF Gel - Product Status 98
Table 88: HYAFF Gel - Product Description 98
Table 89: HYAFF/ACP Spray - Adhesion - Product Status 98
Table 90: HYAFF/ACP Spray - Adhesion - Product Description 99
Table 91: Hyaloglide - Product Status 99
Table 92: Hyaloglide - Product Description 99
Table 93: ApoPharma Inc Pipeline Products & Ongoing Clinical Trials Overview 100
Table 94: Dermal - LSR - Product Status 100
Table 95: Dermal - LSR - Product Description 100
Table 96: ARC Medical Devices Inc. Pipeline Products & Ongoing Clinical Trials Overview 101
Table 97: Peridan Concentrate - Product Status 101
Table 98: Peridan Concentrate - Product Description 101
Table 99: Aroa Biosurgery Ltd Pipeline Products & Ongoing Clinical Trials Overview 102
Table 100: Endoform Breast Device - Product Status 102
Table 101: Endoform Breast Device - Product Description 102
Table 102: Endoform Infection Control - Product Status 103
Table 103: Endoform Infection Control - Product Description 103
Table 104: Arsenal Medical Inc Pipeline Products & Ongoing Clinical Trials Overview 104
Table 105: Arsenal Foam System - Abdominal Aortic Aneurysm - Product Status 104
Table 106: Arsenal Foam System - Abdominal Aortic Aneurysm - Product Description 105
Table 107: ResQFoam - Product Status 105
Table 108: ResQFoam - Product Description 106
Table 109: Arsenal Medical Inc - Ongoing Clinical Trials Overview 107
Table 110: ResQFoam - Reducing Exsanguination via In-vivo Expandable Foam (REVIVE) 107
Table 111: Arteriocyte Medical Systems Inc Pipeline Products & Ongoing Clinical Trials Overview 108
Table 112: Magellan Autologous Platelet Gel - Product Status 108
Table 113: Magellan Autologous Platelet Gel - Product Description 108
Table 114: Magellan Bio-Bandage - Acute Deep Partial Thickness Thermal Injuries - Product Status 109
Table 115: Magellan Bio-Bandage - Acute Deep Partial Thickness Thermal Injuries - Product Description 109
Table 116: Arteriocyte Medical Systems Inc - Ongoing Clinical Trials Overview 110
Table 117: Magellan Autologous Platelet Gel - Effectiveness of Autologous Platelet Rich Plasma in the Treatment of Chronic Skin Wounds 110
Table 118: Magellan Autologous Platelet Gel - Phase I, Non-randomized, Feasibility Study for the Use of Bone Marrow Cell Concentrate Prepared Using the Magellan System for the Treatment of Critical Limb Ischemia 111
Table 119: Magellan Autologous Platelet Gel - Use of Autologous Platelet Rich Plasma (PRP) Gel as an Adjunct to the Treatment of Deep Second and Third Degree Burns 111
Table 120: Magellan Bio-Bandage - Acute Deep Partial Thickness Thermal Injuries - Phase I, Double-blind, Randomized, Controlled Study to Demonstrate the Safety of Applying Autologous Platelet Rich Plasma (PRP) Gel (Magellan Bio-Bandage) to Acute Deep Partial Thickness Thermal Injuries 112
Table 121: Asana Medical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 113
Table 122: ExtraCellular Matrix Hydrogel - Product Status 113
Table 123: ExtraCellular Matrix Hydrogel - Product Description 113
Table 124: Aspen Surgical Products Pipeline Products & Ongoing Clinical Trials Overview 114
Table 125: Transparent Film Dressing - Product Status 114
Table 126: Transparent Film Dressing - Product Description 114
Table 127: Avita Medical Ltd Pipeline Products & Ongoing Clinical Trials Overview 115
Table 128: ReGenerCell - Diabetic Foot Ulcers - Product Status 115
Table 129: ReGenerCell - Diabetic Foot Ulcers - Product Description 116
Table 130: ReGenerCell - Venous Leg Ulcers - Product Status 116
Table 131: ReGenerCell - Venous Leg Ulcers - Product Description 117
Table 132: Avita Medical Ltd - Ongoing Clinical Trials Overview 117
Table 133: ReGenerCell - Diabetic Foot Ulcers - A Feasibility Study of the ReGenerCell Autologous Cell Harvesting Device for Diabetic Foot Ulcers 117
Table 134: Axcelon Biopolymers Corp. Pipeline Products & Ongoing Clinical Trials Overview 118
Table 135: Nanoderm Plus - Product Status 118
Table 136: Nanoderm Plus - Product Description 118
Table 137: Baxter International Inc Pipeline Products & Ongoing Clinical Trials Overview 119
Table 138: Veritas - Cardiac Application - Product Status 119
Table 139: Veritas - Cardiac Application - Product Description 120
Table 140: Bayer HealthCare AG Pipeline Products & Ongoing Clinical Trials Overview 121
Table 141: Analgesic Coated Silica Gel Fiber - Product Status 121
Table 142: Analgesic Coated Silica Gel Fiber - Product Description 121
Table 143: Silica Gel Wound Dressing - Product Status 122
Table 144: Silica Gel Wound Dressing - Product Description 122
Table 145: BioCure, Inc. Pipeline Products & Ongoing Clinical Trials Overview 123
Table 146: BCNP - Product Status 123
Table 147: BCNP - Product Description 123
Table 148: Growth Factor Delivery - Hydrogel Wound Dressing - Product Status 124
Table 149: Growth Factor Delivery - Hydrogel Wound Dressing - Product Description 124
Table 150: Spray-On Dressings - Product Status 124
Table 151: Spray-On Dressings - Product Description 125
Table 152: Biomendics, LLC Pipeline Products & Ongoing Clinical Trials Overview 126
Table 153: Wound Gel - Product Status 126
Table 154: Wound Gel - Product Description 126
Table 155: BioPhotas, Inc. Pipeline Products & Ongoing Clinical Trials Overview 127
Table 156: Celluma - Dermal Wound Healing - Product Status 127
Table 157: Celluma - Dermal Wound Healing - Product Description 127
Table 158: BioRegenerative Sciences, Inc. Pipeline Products & Ongoing Clinical Trials Overview 128

1.2 List of Figures
Figure 1: Advanced Wound Management - Pipeline Products by Stage of Development 44
Figure 2: Advanced Wound Management - Pipeline Products by Segment 45
Figure 3: Advanced Wound Management - Pipeline Products by Territory 46
Figure 4: Advanced Wound Management - Pipeline Products by Regulatory Path 48
Figure 5: Advanced Wound Management - Pipeline Products by Estimated Approval Date 49
Figure 6: Advanced Wound Management - Ongoing Clinical Trials 50