ArQule, Inc. - Product Pipeline Review - 2014

Global Markets Direct
April 30, 2014
44 Pages - GMD12106


Global Markets Direct’s, ‘ArQule, Inc. - Product Pipeline Review - 2014’, provides an overview of the ArQule, Inc.’s pharmaceutical research and development focus.

This report provides comprehensive information on the current therapeutic developmental pipeline of ArQule, Inc.’s, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews latest updates, and featured news and press releases, along with special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.


- The report provides brief overview of ArQule, Inc. including business description, key information and facts, and its locations and subsidiaries
- The report reviews current pipeline of ArQule, Inc.’s human therapeutic division and enlists all their major and minor projects
- The report features product description and descriptive mechanism of action for key pipeline products along with the product’s developmental history and major milestones
- Special feature on out-licensed and partnered product portfolio
- The report summarizes all the dormant and discontinued pipeline projects
- Latest company statement
- Latest news and deals relating to the ArQule, Inc.’s pipeline products

Reasons to buy

- Evaluate ArQule, Inc.’s strategic position with total access to detailed information on its product pipeline
- Assess the growth potential of ArQule, Inc. in its therapy areas of focus
- Identify new drug targets and therapeutic classes in the ArQule, Inc.’s R&D portfolio and develop key strategic initiatives to reinforce pipeline in those areas
- Exploit in-licensing opportunities by identifying windows of opportunity to fill portfolio gaps
- Develop strategic initiatives by understanding the focus areas of ArQule, Inc. and exploit collaboration and partnership opportunities
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Plan mergers and acquisitions effectively by identifying the most promising pipeline of ArQule, Inc.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Explore the dormant and discontinued projects of ArQule, Inc. and identify potential opportunities in those areas
- Avoid Intellectual Property Rights related issues


Table of Contents
Table of Contents 2
List of Tables 4
List of Figures 4
ArQule, Inc. Snapshot 5
ArQule, Inc. Overview 5
Key Information 5
Key Facts 5
ArQule, Inc. - Research and Development Overview 6
Key Therapeutic Areas 6
ArQule, Inc. - Pipeline Review 9
Pipeline Products by Stage of Development 9
Pipeline Products - Monotherapy 10
ArQule, Inc. - Pipeline Products Glance 11
ArQule, Inc. - Late Stage Pipeline Products 11
Phase III Products/Combination Treatment Modalities 11
ArQule, Inc. - Clinical Stage Pipeline Products 12
Phase II Products/Combination Treatment Modalities 12
Phase I Products/Combination Treatment Modalities 13
ArQule, Inc. - Early Stage Pipeline Products 14
Discovery Products/Combination Treatment Modalities 14
ArQule, Inc. - Drug Profiles 15
tivantinib 15
Product Description 15
Mechanism of Action 15
R&D Progress 15
ARQ-087 18
Product Description 18
Mechanism of Action 18
R&D Progress 18
ARQ-092 19
Product Description 19
Mechanism of Action 19
R&D Progress 19
ARQ-621 20
Product Description 20
Mechanism of Action 20
R&D Progress 20
ARQ-736 21
Product Description 21
Mechanism of Action 21
R&D Progress 21
ARQ-761 22
Product Description 22
Mechanism of Action 22
R&D Progress 22
Small Molecules To Inhibit Kinase For Oncology 23
Product Description 23
Mechanism of Action 23
R&D Progress 23
ArQule, Inc. - Pipeline Analysis 24
ArQule, Inc. - Pipeline Products by Target 24
ArQule, Inc. - Pipeline Products by Route of Administration 26
ArQule, Inc. - Pipeline Products by Molecule Type 27
ArQule, Inc. - Pipeline Products by Mechanism of Action 28
ArQule, Inc. - Recent Pipeline Updates 30
ArQule, Inc. - Dormant Projects 35
ArQule, Inc. - Discontinued Pipeline Products 36
Discontinued Pipeline Product Profiles 36
ARQ-171 36
tivantinib 36
ArQule, Inc. - Company Statement 37
ArQule, Inc. - Locations And Subsidiaries 42
Head Office 42
Appendix 43
Methodology 43
Coverage 43
Secondary Research 43
Primary Research 43
Expert Panel Validation 43
Contact Us 44
Disclaimer 44

List of Tables
ArQule, Inc., Key Information 5
ArQule, Inc., Key Facts 5
ArQule, Inc. - Pipeline by Indication, 2014 8
ArQule, Inc. - Pipeline by Stage of Development, 2014 9
ArQule, Inc. - Monotherapy Products in Pipeline, 2014 10
ArQule, Inc. - Phase III, 2014 11
ArQule, Inc. - Phase II, 2014 12
ArQule, Inc. - Phase I, 2014 13
ArQule, Inc. - Discovery, 2014 14
ArQule, Inc. - Pipeline by Target, 2014 25
ArQule, Inc. - Pipeline by Route of Administration, 2014 26
ArQule, Inc. - Pipeline by Molecule Type, 2014 27
ArQule, Inc. - Pipeline Products by Mechanism of Action, 2014 29
ArQule, Inc. - Recent Pipeline Updates, 2014 30
ArQule, Inc. - Dormant Developmental Projects, 2014 35
ArQule, Inc. - Discontinued Pipeline Products, 2014 36

List of Figures
ArQule, Inc. - Pipeline by Top 10 Indication, 2014 7
ArQule, Inc. - Pipeline by Stage of Development, 2014 9
ArQule, Inc. - Monotherapy Products in Pipeline, 2014 10
ArQule, Inc. - Pipeline by Top 10 Target, 2014 24
ArQule, Inc. - Pipeline by Top 10 Route of Administration, 2014 26
ArQule, Inc. - Pipeline by Top 10 Molecule Type, 2014 27
ArQule, Inc. - Pipeline Products by Top 10 Mechanism of Action, 2014 28


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